1,680 research outputs found

    Droplets displacement and oscillations induced by ultrasonic surface acoustic waves: a quantitative study

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    We present an experimental study of a droplet interacting with an ultrasonic surface acoustic wave (SAW). Depending on the amplitude of the wave, the drop can either experience an internal flow with its contact-line pinned, or (at higher amplitude) move along the direction of the wave also with internal flow. Both situations appear together with oscillations of the drop free-surface. The physical origins of the internal mixing flow as well as the drop displacement and surface waves are still not well understood. In order to give insights of the underlying physics involved in these phenomena, we carried out an experimental and numerical study. The results suggest that the surface deformation of the drop can be related as a combination between acoustic streaming effect and radiation pressure inside the drop.Comment: 9 pages, 14 figures. To appear in Physical Review

    Exploring a syntactic notion of modal many-valued logics

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    We propose a general semantic notion of modal many-valued logic. Then, we explore the di culties to characterize this notion in a syntactic way and analyze the existing literature with respect to this frameworkPeer Reviewe

    The physics of wind-blown sand and dust

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    The transport of sand and dust by wind is a potent erosional force, creates sand dunes and ripples, and loads the atmosphere with suspended dust aerosols. This article presents an extensive review of the physics of wind-blown sand and dust on Earth and Mars. Specifically, we review the physics of aeolian saltation, the formation and development of sand dunes and ripples, the physics of dust aerosol emission, the weather phenomena that trigger dust storms, and the lifting of dust by dust devils and other small-scale vortices. We also discuss the physics of wind-blown sand and dune formation on Venus and Titan.Comment: 72 journal pagers, 49 figure

    Plantes transgèniques en recerca

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    El conjunt d'aproximacions presentades en aquest article il·lustra alguns dels usos més habituals de les plantes transgèniques en la recerca, que han permès, i encara permeten, respondre moltes preguntes genuïnes de gran interès biològic difícilment resolubles per altres aproximacions. Per això es pot afirmar que les plantes transgèniques han revolucionat la recerca bàsica i aplicada en el camp de la biologia vegetal. La seua utilització ens està ajudant a entendre millor com uns organismes tan fascinants i plàstics com les plantes es formen i, en interaccionar amb el medi, responen alterant la seua forma o fisiologia. Encara ens queda molt per conèixer, i l'ús de plantes transgèniques en la nostra recerca encara té molt a dir. Esbrinar més o menys depèn, en gran mesura, de la imaginació dels investigadors.The different strategies summarized in the manuscript illustrate some of the most common uses of transgenic plants in research. They have allowed answering several questions of great biological importance that cannot be easily addressed by other approaches. For that reason it is probably correct to state that transgenic plants have revolutionized basic and applied research in plant biology. Its utilization is helping us to better understand how these fascinating and plastic organisms are formed and, when interacting with the environment, responding by changing their form and/or physiology. We still have a lot to learn, and usage of transgenic plants in our research still has a lot to give. To discover more or less depends, partially, on the imagination of researchers

    Clinical review: Liberation from mechanical ventilation

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    Mechanical ventilation is the defining event of intensive care unit (ICU) management. Although it is a life saving intervention in patients with acute respiratory failure and other disease entities, a major goal of critical care clinicians should be to liberate patients from mechanical ventilation as early as possible to avoid the multitude of complications and risks associated with prolonged unnecessary mechanical ventilation, including ventilator induced lung injury, ventilator associated pneumonia, increased length of ICU and hospital stay, and increased cost of care delivery. This review highlights the recent developments in assessing and testing for readiness of liberation from mechanical ventilation, the etiology of weaning failure, the value of weaning protocols, and a simple practical approach for liberation from mechanical ventilation

    A Paradox of State-Dependent Diffusion and How to Resolve It

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    Consider a particle diffusing in a confined volume which is divided into two equal regions. In one region the diffusion coefficient is twice the value of the diffusion coefficient in the other region. Will the particle spend equal proportions of time in the two regions in the long term? Statistical mechanics would suggest yes, since the number of accessible states in each region is presumably the same. However, another line of reasoning suggests that the particle should spend less time in the region with faster diffusion, since it will exit that region more quickly. We demonstrate with a simple microscopic model system that both predictions are consistent with the information given. Thus, specifying the diffusion rate as a function of position is not enough to characterize the behaviour of a system, even assuming the absence of external forces. We propose an alternative framework for modelling diffusive dynamics in which both the diffusion rate and equilibrium probability density for the position of the particle are specified by the modeller. We introduce a numerical method for simulating dynamics in our framework that samples from the equilibrium probability density exactly and is suitable for discontinuous diffusion coefficients.Comment: 21 pages, 6 figures. Second round of revisions. This is the version that will appear in Proc Roy So

    Determination of total plasma hydroperoxides using a diphenyl-1- pyrenylphosphine fluorescent probe

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    Plasma hydroperoxides (HPs) are widely accepted to be good indicators of oxidative stress. By means of the method proposed here, which uses diphenyl-1-pyrenylphosphine (DPPP) as a fluorescent probe, all types of plasma HP were determined. The limits of detection and quantification of the method were 0.08 and 0.25 nmol of cumene hydroperoxide (CHP) equivalents in 40 μl of plasma, respectively. The method is satisfactory in terms of precision (5.3% for 14.5 μM CHP eq., n = 8), and the recoveries were 91% and 92% after standard additions of 26 and 52 μM CHP, respectively. The selectivity of the proposed method is higher than 96%. Moreover, optimization of the reaction conditions and the addition of ethylenediaminetetraacetic acid (EDTA) disodium salt and 2,6-di-tert-butyl-4-methylphenol (BHT) prevented the formation of HP artifacts during the analysis. Therefore, the proposed method is useful for simple and quantitative determination of total plasma HPs. © 2012 Elsevier Inc. All rights reserved.Peer Reviewe

    Cayley modification for strongly stable path-integral and ring-polymer molecular dynamics

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    Path-integral-based molecular dynamics (MD) simulations are widely used for the calculation of numerically exact quantum Boltzmann properties and approximate dynamical quantities. A nearly universal feature of MD numerical integration schemes for equations of motion based on imaginary-time path integrals is the use of harmonic normal modes for the exact evolution of the free ring-polymer positions and momenta. In this work, we demonstrate that this standard practice creates numerical artifacts. In the context of conservative (i.e., microcanonical) equations of motion, it leads to numerical instability. In the context of thermostated (i.e., canonical) equations of motion, it leads to nonergodicity of the sampling. These pathologies are generally proven to arise at integration time steps that depend only on the system temperature and the number of ring-polymer beads, and they are numerically demonstrated for the cases of conventional ring-polymer MD (RPMD) and thermostated RPMD (TRPMD). Furthermore, it is demonstrated that these numerical artifacts are removed via replacement of the exact free ring-polymer evolution with a second-order approximation based on the Cayley transform. The Cayley modification introduced here can immediately be employed with almost every existing integration scheme for path-integral-based MD—including path-integral MD (PIMD), RPMD, TRPMD, and centroid MD—providing strong symplectic stability and ergodicity to the numerical integration, at no penalty in terms of computational cost, algorithmic complexity, or accuracy of the overall MD time step. Furthermore, it is shown that the improved numerical stability of the Cayley modification allows for the use of larger MD time steps. We suspect that the Cayley modification will therefore find useful application in many future path-integral-based MD simulations

    Cayley modification for strongly stable path-integral and ring-polymer molecular dynamics

    Get PDF
    Path-integral-based molecular dynamics (MD) simulations are widely used for the calculation of numerically exact quantum Boltzmann properties and approximate dynamical quantities. A nearly universal feature of MD numerical integration schemes for equations of motion based on imaginary-time path integrals is the use of harmonic normal modes for the exact evolution of the free ring-polymer positions and momenta. In this work, we demonstrate that this standard practice creates numerical artifacts. In the context of conservative (i.e., microcanonical) equations of motion, it leads to numerical instability. In the context of thermostated (i.e., canonical) equations of motion, it leads to nonergodicity of the sampling. These pathologies are generally proven to arise at integration time steps that depend only on the system temperature and the number of ring-polymer beads, and they are numerically demonstrated for the cases of conventional ring-polymer MD (RPMD) and thermostated RPMD (TRPMD). Furthermore, it is demonstrated that these numerical artifacts are removed via replacement of the exact free ring-polymer evolution with a second-order approximation based on the Cayley transform. The Cayley modification introduced here can immediately be employed with almost every existing integration scheme for path-integral-based MD—including path-integral MD (PIMD), RPMD, TRPMD, and centroid MD—providing strong symplectic stability and ergodicity to the numerical integration, at no penalty in terms of computational cost, algorithmic complexity, or accuracy of the overall MD time step. Furthermore, it is shown that the improved numerical stability of the Cayley modification allows for the use of larger MD time steps. We suspect that the Cayley modification will therefore find useful application in many future path-integral-based MD simulations
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